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In contrast, in AD, MAFG has been suggested to not be upregulated whereas a different sMAF protein (MAFF) has been suggested to be the most responsive sMAF protein to AD pathology 133โ135 , though the cellular source of MAFF in AD has not been determined yet
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In Caenorhabditis elegans, rnp-6 (RNA-binding domain-containing protein 6) encodes the sole ortholog of human PUF60 18
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