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dimeric glutathione reductase Identification of novel thiadiazin derivatives as potentially selective inhibitors towards trypanothione from Trypanosoma cruzi by molecular docking using the numerical index poses ratio Pr and the binding mode analysis glutathione reductase mechanism
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When GCDH is knocked down in melanoma cells, it leads to increased glutarylation of NRF2, a transcription factor that becomes stabilized and transcriptionally active
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