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A 2020 review by Islam, Hood, and Gurd in Applied Physiology, Nutrition, and Metabolism catalogued the regulators of exercise-induced skeletal muscle mitochondrial biogenesis beyond PGC-1α and identified ERRα as one of the key downstream effectors

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When transplanted into NOD SCID mice, as few as 20 of these CD8+TCF1 high stem-like T cells could induce T1D while as many as 100,000 TCF1 low cells did not (38)