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While the Ξ±1Ξ²2Ξ³2 GABA A R subtype, accounting for βΌ43% of all GABA A Rs, is expressed by GABAergic interneurons and pyramidal cells more or less ubiquitously within the brain [96], the other GABA A R subtypes are specific for particular brain structures: Ξ±1Ξ²2,3Ξ³2 GABA A R is characteristic for aspiny cells and Ξ±2/Ξ±3Ξ²2,3Ξ³2 for PyCs of the amygdala [97], Ξ±4Ξ²Ξ΄ GABA A R [98] and Ξ±5Ξ²3Ξ³2/Ξ³3 [99] are found in hippocampal PyCs, and Ξ±6-containing GABA A Rs are restricted to differentiated cerebellar granule cells [100]
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