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The FDA publishes those disclosures in the Orange Book, and ANDA applicants must then certify their position on each listed patent through one of four certifications: Paragraph I (patent not applicable), Paragraph II (patent expired), Paragraph III (applicant will wait for patent expiration), or Paragraph IV (patent is invalid or will not be infringed by the generic)
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46 The decreased levels of GSH in PCOS cases would possibly require the activation of the redox GSH cycle by activating GPx and GR enzymes to enhance the production of functional GSH
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