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Hydroxychloroquine inhibits the mitochondrial antioxidant system in activated T cells - ScienceDirect
Based on these findings, we proposed the following therapeutic strategies: First, targeting key metabolic reprogramming pathways (such as oxidative phosphorylation and glycolysis) and developing drugs targeting NDUFAB1 or ELK4 specifically disrupted the metabolic hub of this subtype, effectively inhibiting its energy supply and consequently limiting its proliferation
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