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Partially protected peptide 4a was dissolved in 2,2,2-trifluoroethanol and hydrogenated in the presence of palladium on charcoal (10%) with hydrogen gas at 30°C

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Although ibuprofen is available over the counter, the FDA warns that it can cause serious side effects — including stomach bleeding, kidney damage and cardiovascular complications — especially when used at high doses or for long periods

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