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Strigolactones: Coordination with other phytohormones and enhancement of abiotic stress responses - ScienceDirect

Indeed, despite the availability of original safety data on the previous approved indication, to receive marketing authorization, the repurposed drugs need to be tested for their efficacy, safety, and tolerability in clinical trials

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These differences can arise from the nature of the standards used, from sample loss due to the volatility and oxidation lability of H 2 S, from interference from species with similar reactivity (e.g., thiols and persulfides), and from the release of H 2 S from labile pools during sample handling (e.g., acidification, alkalinization, reduction)