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By employing the hypergeometric distribution, the probability of a frequency greater than k under completely random conditions was calculated using the following formula: p=1–∑i=0k–1p(i|n,m,N) where, p(i|n,m,N)=n!(N–n)!m!(N–m)!(n–i)!i!(n–m)!(N–n–m+i)!N

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