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This leads to damage to tissue cells, including vascular ECs (Incalza et al., 2018), adipocytes (Furukawa et al., 2004), and pancreatic β-cells (Gerber and Rutter, 2017)
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▪ NAD+ / SIRT1: Associated with elevated NAD+ and SIRT1 activation in preclinical studies [2] [3]
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