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Male use, off-label Although Vyleesi is approved only for women, PT-141 is also studied in research contexts in men , particularly for indications: Erectile dysfunction (where PDE5 inhibitors do not work well, especially neurogenic forms) PSSD (Post-SSRI Sexual Dysfunction), persistent sexual dysfunction after discontinuation of antidepressants Anorgasmia Low libido in men with normal testosterone These uses are not formally approved , but several clinical trials are ongoing
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