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AHK-Cu (Ala-His-Lys-Cu) is a related copper tripeptide found in human plasma that shares the His-Lys copper-binding motif but substitutes alanine for glycine at the N-terminal position, resulting in a slightly different copper coordination geometry and a distinct (though overlapping) gene expression modulation profile
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TREK-1 (TWIK related potassium channel) receptor is a two pore potassium channel that was recently identified as a potential target to treat depression
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