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As a fatty-acid–acylated analogue of human amylin (islet amyloid polypeptide, IAPP), cagrilintide has been engineered to exhibit prolonged receptor engagement and improved pharmacokinetic stability relative to native amylin, making it particularly well-suited for longitudinal preclinical study designs where sustained receptor occupancy is required
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[PMC free article] [PubMed] [Google Scholar] 37.Yang T, Yang Y, Wang D, Li C, Qu Y, Guo J, et al
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