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Similar results were obtained with mRNA expression of MMP-2 ( P =0.01), stromal-derived factor-1 (SDF-1) ( P =0.01), tumor growth factor (TGF)- β ( P =0.001) and poly-(ADP-ribose) polymerase (PARP) that occurs in response to DNA damage ( P =0.001) (Figure 5b)
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Vitamin C is ultimately essential in this process because not only does it help produce NADPH but it also regulates the quantities so the white blood cell does not create excessive oxidative stress in its attempt to protect the body
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