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MRI data suggested a potential modest increase in hippocampal volume in NSI-189-treated patients, which would be in line with the postulated neurogenetic mechanism underlying NSI-189 treatment, but this was not significant and was not different from the changes observed on the small cohort on placebo, and are purely provided for descriptive purposes
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13 , 22 , 23 , 105 , 107 , 108 , 115 , 121 In incident dialysis patients, roxadustat treatment without iron supplementation resulted in an initial Hb increase
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