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In a study by Tanaka et al ., over-expression of both wild type and mutant α-synuclein inhibited the activity of UPS in dopaminergic PC12 cells [361]
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Moreover, in IFN-γ-stimulated RAW 264.7 macrophages, gliadin increases iNOS gene expression through a mechanism involving NF-κB and other transcription factors (IRF-1 and STAT-1α) [57,66] (Figure 2)
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