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Efficacy of oral compared with intramuscular vitamin B-12 supplementation after Roux-en-Y gastric bypass: a randomized controlled trial - ScienceDirect
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By blocking NNMT, 5-Amino-1MQ keeps more nicotinamide available, which animal and cell models show increases intracellular NAD+ pools by 1.2 to 1.6 fold , enhancing mitochondrial energy output
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