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Given our findings that exogenous acyl-GIP-induced reductions in lipid excursions during LTTs may be mediated through increases in BAT fatty acid uptake and LPL activity, we assessed how BAT GIPR signaling contributes to whole-body lipid tolerance, energy expenditure, and fatty acid oxidation using obese Gipr BAT−/− ( Gipr knockout) and littermate controls ( Gipr BAT+/+
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