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This has even been achieved in lower eukaryotes such as Saccharomyces cerevisiae , where a significant resistance to chlorambucil and doxorubicin (eight- and 16-fold, respectively) was reported in cells transfected with mammalian GST isozymes (Black et al ., 1990)

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While BPC-157 has a strong safety record in animal studies, there are currently no long-duration, placebo-controlled human trials available to confirm its effects over months or years