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W części badań na zwierzętach i we wczesnych próbach u ludzi opisywano wpływ na udział snu wolnofalowego, jednak w innych, lepiej kontrolowanych badaniach efektu tego nie udało się replikować
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1 3 The genetic proof of concept used a complementary approach — antisense knockdown to remove NNMT rather than a drug to block it — which strengthens causal inference because two independent methods (genetic and pharmacological) converge on the same phenotype
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