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10.1016/j.neuroscience.2010.11.007 81 ValkoM.IzakovicM.MazurM.RhodesC

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Busulfan metabolism was modeled as a GSH-dependent conjugation process, with the scaling parameter S GSH quantifying the proportionality between busulfan metabolism and corresponding GSH depletion (Equation 2).Where represents the amount of busulfan in the central compartment, represents the amount of GSH in the theoretical compartment, represents the central volume of distribution, and represents the busulfan elimination constant

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