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Activation of the IL6 inflammatory loop may mediate trastuzumab resistance in human epidermal growth factor receptor 2-positive breast cancer by promoting growth of the cancer stem cell population (72)
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Moreover, SCFAs reduce the progression of NAFLD by inducing liver autophagy through the PPARγ-UCP2-AMPK pathway, which could be a novel treatment approach (Li et al., 2024c)
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