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The increase in glutamate secondary to consumption of MSG encouraged Ca 2+ inflow and disturbance of the inner mitochondrial transmembrane potential, which resulted in opening the mitochondria permeability transition pore (Khodorov et al., 2002
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Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65
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