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GHK-Cu's Documented Effects on TNF-α Published research has documented GHK-Cu's modulating effects on TNF-α in research models: Reductions in TNF-α expression in inflammatory tissue models Decreased TNF-α release from inflammatory cells in cell culture studies TNF-α modulation as part of GHK-Cu's broader gene expression effects (TNF-α gene expression is among the hundreds of genes documented in GHK-Cu microarray studies) Anti-inflammatory effects in wound healing and skin biology research contexts The TNF-α modulation appears to be part of GHK-Cu's broader pattern of gene expression effects rather than a single-target mechanism

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[DOI] [PubMed] [Google Scholar] 106.Ma H, Hong M, Duan J, Liu P, Fan X, Shang E, Su S, Guo J, Qian D, Tang Y