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Mechanism of action The mechanism of action of paracetamol is not well understood, but it may act in a similar fashion to NSAIDs, with inhibition of cyclo-oxygenase enzymes COX-1 and COX-2 to reduce the phenoxyl radical formation required for COX-1 and 2 activity and prostaglandin synthesis
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These “ melasma on face types ” include: Centrofacial: This is the most common pattern, affecting the forehead, nose, upper lip, cheeks, and chin
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