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Cation selectivity of the presequence translocase channel Tim23 is crucial for efficient protein import
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Similarly, activation of the optogenetic chloride pump halorhodopsin induces neuronal hyperpolarization, which secondarily drives potassium ions into cells, lowering extracellular potassium concentration and indirectly inhibiting neighboring non-expressing neurons, demonstrating a network-wide inhibitory effect (Parrish et al., 2023)
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