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🔬 What researchers observed in obese mice: • Less body-weight and fat-mass gain • Improved glucose tolerance and insulin sensitivity • Reduced hyperinsulinemia • Improvement in fatty-liver findings • No reduction in food intake in the studied animals These findings make NNMT inhibition an interesting metabolic research target—but they remain preclinical animal findings, not proven human results

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The pharmaceutical research literature has increasingly explored combinations of GLP-1 agonists with amylin analogs (combining semaglutide with cagrilintide)