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LDN - 4.5 to 6 mg in the evening My Personal Story with LDN I first became interested in LDN in 2011 when it was reported by an online patient survey as one of the most effective treatments for ME and FM

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In a 68- and 72-week clinical trial studying Wegovy (2.4 mg), brand-name Semaglutide, and Zepbound (15 mg), brand-name Tirzepatide, in patients without diabetes and with BMI ≥30, or BMI ≥27 with a weight-related condition, the average weight loss was 15% and 20% respectively, when paired with diet and exercise changes (compared to 2.4% and 3.1%, respectively, with diet and exercise alone)