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A comparison of copper binding properties, copper exchange rate and redox potential between two similar naturally occurring copper-binding peptides GHK and DAHK shows that even though both bind copper in stoichiometry at a ratio of 1:1, the exchange rate of copper between DAHK peptides is very slow, while the exchange rate between GHK peptides is much faster
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Moreover, acrolein itself can inactivate ALDH2 activity by forming adduct at its NAD binding site [32]
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