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In MPTP-induced PD mouse models, apoferritin downregulated the expression of DMT1 and ACSL4 while upregulating FSP1 expression, without affecting GPX4 levels, thereby preventing ferroptosis [78]
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Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers
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