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the EC 50 value of the target cell surface antigenxCD3 bispecific antibody construct is preferably ⁇ 5000 pM or ⁇ 4000 pM (in particular when the target cells are target cell surface antigen positive human cell lines), more preferably ⁇ 2000 pM (in particular when the target cells are target cell surface antigen transfected cells such as CHO cells), more preferably ⁇ 1000 pM or ⁇ 500 pM, even more preferably ⁇ 200 pM, even more preferably ⁇ 150 pM, even more preferably ⁇ 100 pM, and most preferably ⁇ 50 pM, or lower

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