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Evaluating Concentration-Dependent Vermiwash Effects on Seedling Performance, Soil Biochemical Functioning, and Nutrient Dynamics of Solanum melongena L. | Journal of Soil Science and Plant Nutrition | Springer Nature Link

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For prostanoid generation, both COX-1, which is constitutively expressed by most cells, and COX-2, an inducible isoform upregulated by inflammatory mediators such as lipopolysaccharide, IL-1β, IL-6, or tumor necrosis factor-α (TNF-α), convert AA into prostaglandin endoperoxides (PGs), such as prostaglandin G 2 (PGG 2 ) ( 2 to PGH 2 , a highly unstable cyclic endoperoxide that is rapidly converted into bioactive prostanoids by specific synthases, including PGD 2 , PGE 2 , PGF 2α , PGI 2 , and TxA 2 (Zaslona and Peters-Golden, 2015)