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Crystallization Mutants (see above) of hTrxR1, complexed with hTrx1 in 50 mM Tris-HCl, 200 mM NaCl, 1 mM EDTA, pH 7.6, were concentrated to 10 mg ml −1

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It is important to emphasize, however, that human data for BPC-157 are extremely limited: only three pilot studies have examined the peptide in humans, including applications for intraarticular knee pain, interstitial cystitis, and an intravenous safety/pharmacokinetics study