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In wild type mice, MOR recovery was slow after ME-induced desensitization (approximately 60 minutes), similar to results reported earlier for locus coeruleus neurons from rat (Osborne and Williams, 1995
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Current treatments for AD, such as acetylcholinesterase inhibitors (e.g., donepezil) and NMDA receptor antagonists (e.g., memantine), provide symptomatic relief but do not halt or reverse disease progression
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